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Query Molecule
Export table:  
Known actives on Dopamine D2 receptor, similar in 2D
CHEMBL143509
Similarity: 0.673
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL363932
Similarity: 0.648
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL186229
Similarity: 0.632
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL2377591
Similarity: 0.628
CHEMBL186173
Similarity: 0.622
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL187196
Similarity: 0.617
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL396560
Similarity: 0.615
CHEMBL2377443
Similarity: 0.614
CHEMBL3622096
Similarity: 0.607
CHEMBL61747
Similarity: 0.607
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL63063
Similarity: 0.606
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL396561
Similarity: 0.605
CHEMBL185779
Similarity: 0.602
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL393275
Similarity: 0.601
CHEMBL186409
Similarity: 0.598
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL3622098
Similarity: 0.596
CHEMBL34022
Similarity: 0.596
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL34025
Similarity: 0.596
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL3753318
Similarity: 0.583
CHEMBL13866
Similarity: 0.581
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL362771
Similarity: 0.581
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL3754166
Similarity: 0.579
CHEMBL391190
Similarity: 0.578
CHEMBL14138
Similarity: 0.576
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL308143
Similarity: 0.575
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL245571
Similarity: 0.574
CHEMBL143767
Similarity: 0.571
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL76237
Similarity: 0.568
CHEMBL13811
Similarity: 0.567
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL245570
Similarity: 0.566
CHEMBL433233
Similarity: 0.563
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL143510
Similarity: 0.562
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL59335
Similarity: 0.562
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL188408
Similarity: 0.561
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL245764
Similarity: 0.560
CHEMBL319005
Similarity: 0.558
CHEMBL328476
Similarity: 0.558
CHEMBL143967
Similarity: 0.557
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL59940
Similarity: 0.557
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL130327
Similarity: 0.556
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL3752900
Similarity: 0.556
CHEMBL366271
Similarity: 0.555
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL142163
Similarity: 0.552
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL196132
Similarity: 0.547
CHEMBL188296
Similarity: 0.547
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL143512
Similarity: 0.546
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL554027
Similarity: 0.544
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL59737
Similarity: 0.544
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL3754496
Similarity: 0.541
CHEMBL1949725
Similarity: 0.540
CHEMBL306197
Similarity: 0.537
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL13048
Similarity: 0.535
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL1794999
Similarity: 0.535
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL3799455
Similarity: 0.534
CHEMBL363055
Similarity: 0.532
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL1185
Similarity: 0.532
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL2207484
Similarity: 0.532
CHEMBL60267
Similarity: 0.527
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL110032
Similarity: 0.524
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL1173363
Similarity: 0.524
CHEMBL347291
Similarity: 0.524
CHEMBL189758
Similarity: 0.523
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL3622097
Similarity: 0.522
CHEMBL3819494
Similarity: 0.521
CHEMBL431367
Similarity: 0.519
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL196505
Similarity: 0.519
CHEMBL136064
Similarity: 0.516
By Homology: Dopamine D2 receptor in Mus musculus

CHEMBL43819
Similarity: 0.515
CHEMBL360419
Similarity: 0.515
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL427523
Similarity: 0.515
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL3622099
Similarity: 0.513
CHEMBL91549
Similarity: 0.513
CHEMBL3286567
Similarity: 0.512
CHEMBL3286568
Similarity: 0.512
CHEMBL3286569
Similarity: 0.512
CHEMBL44310
Similarity: 0.511
CHEMBL531
Similarity: 0.511
CHEMBL1170095
Similarity: 0.511
CHEMBL3409245
Similarity: 0.511
CHEMBL184162
Similarity: 0.511
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL310867
Similarity: 0.510
CHEMBL69562
Similarity: 0.508
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL3286570
Similarity: 0.508
CHEMBL3286571
Similarity: 0.508
CHEMBL3286572
Similarity: 0.508
CHEMBL3286574
Similarity: 0.508
CHEMBL1949728
Similarity: 0.507
CHEMBL1949729
Similarity: 0.507
CHEMBL3409247
Similarity: 0.507
CHEMBL185860
Similarity: 0.507
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL188625
Similarity: 0.504
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL1170096
Similarity: 0.504
CHEMBL60783
Similarity: 0.504
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL196171
Similarity: 0.504
CHEMBL185805
Similarity: 0.504
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL1173711
Similarity: 0.504
CHEMBL3800400
Similarity: 0.504
CHEMBL3800468
Similarity: 0.504
CHEMBL1173366
Similarity: 0.500
CHEMBL216258
Similarity: 0.500
CHEMBL2207485
Similarity: 0.500
CHEMBL2207486
Similarity: 0.500
CHEMBL245614
Similarity: 0.500
CHEMBL460854
Similarity: 0.500
CHEMBL1186488
Similarity: 0.500
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL188184
Similarity: 0.500
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL313095
Similarity: 0.500
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL366504
Similarity: 0.497
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL198107
Similarity: 0.497
CHEMBL305837
Similarity: 0.496
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL3286573
Similarity: 0.496
CHEMBL186654
Similarity: 0.496
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL71899
Similarity: 0.496
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL1169904
Similarity: 0.493
CHEMBL197665
Similarity: 0.493
CHEMBL1170094
Similarity: 0.493
CHEMBL274410
Similarity: 0.493
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL420748
Similarity: 0.493
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL186034
Similarity: 0.492
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL123094
Similarity: 0.492
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL382850
Similarity: 0.492
CHEMBL441618
Similarity: 0.492
CHEMBL1087300
Similarity: 0.492
CHEMBL142956
Similarity: 0.491
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL292274
Similarity: 0.491
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL303339
Similarity: 0.491
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL413105
Similarity: 0.491
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL142056
Similarity: 0.490
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL142154
Similarity: 0.490
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL142684
Similarity: 0.490
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL16410
Similarity: 0.490
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL440819
Similarity: 0.490
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL194240
Similarity: 0.490
CHEMBL1765632
Similarity: 0.490
CHEMBL372735
Similarity: 0.490
CHEMBL1173287
Similarity: 0.489
CHEMBL1200270
Similarity: 0.489
CHEMBL1173288
Similarity: 0.489
CHEMBL439664
Similarity: 0.489
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL216439
Similarity: 0.488
CHEMBL40584
Similarity: 0.488
CHEMBL91197
Similarity: 0.488
CHEMBL91205
Similarity: 0.488
CHEMBL91463
Similarity: 0.488
CHEMBL61539
Similarity: 0.488
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL123640
Similarity: 0.488
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL314888
Similarity: 0.488
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL194844
Similarity: 0.486
CHEMBL364181
Similarity: 0.486
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL14048
Similarity: 0.486
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL46523
Similarity: 0.486
CHEMBL3286576
Similarity: 0.485
CHEMBL440456
Similarity: 0.485
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL273235
Similarity: 0.484
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL64420
Similarity: 0.484
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL308347
Similarity: 0.484
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL70589
Similarity: 0.484
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL71804
Similarity: 0.484
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL332365
Similarity: 0.484
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL370359
Similarity: 0.483
CHEMBL1744041
Similarity: 0.482
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL302171
Similarity: 0.482
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL302172
Similarity: 0.482
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL305341
Similarity: 0.482
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL305976
Similarity: 0.482
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL65196
Similarity: 0.482
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL71409
Similarity: 0.482
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL72285
Similarity: 0.482
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL273526
Similarity: 0.482
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL3286575
Similarity: 0.482
CHEMBL12312
Similarity: 0.481
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL142197
Similarity: 0.481
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL63449
Similarity: 0.481
CHEMBL65274
Similarity: 0.481
CHEMBL93868
Similarity: 0.481
CHEMBL71395
Similarity: 0.481
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL90263
Similarity: 0.480
CHEMBL90739
Similarity: 0.480
CHEMBL551776
Similarity: 0.480
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL328459
Similarity: 0.480
CHEMBL91542
Similarity: 0.480
CHEMBL423706
Similarity: 0.480
CHEMBL263329
Similarity: 0.479
CHEMBL28054
Similarity: 0.479
CHEMBL14239
Similarity: 0.479
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL2377590
Similarity: 0.478
CHEMBL69560
Similarity: 0.478
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL69729
Similarity: 0.478
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL71663
Similarity: 0.478
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL3409235
Similarity: 0.478
CHEMBL122384
Similarity: 0.477
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL188799
Similarity: 0.477
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL62529
Similarity: 0.476
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL279586
Similarity: 0.476
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL356823
Similarity: 0.476
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL14238
Similarity: 0.476
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL267799
Similarity: 0.476
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL247058
Similarity: 0.475
CHEMBL363754
Similarity: 0.474
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL274446
Similarity: 0.474
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL433968
Similarity: 0.473
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL194510
Similarity: 0.470
CHEMBL365605
Similarity: 0.470
CHEMBL189709
Similarity: 0.470
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL363537
Similarity: 0.470
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL430151
Similarity: 0.470
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL193501
Similarity: 0.470
CHEMBL369984
Similarity: 0.470
CHEMBL186655
Similarity: 0.470
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL303921
Similarity: 0.469
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL53170
Similarity: 0.469
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL198812
Similarity: 0.469
CHEMBL432713
Similarity: 0.469
CHEMBL14020
Similarity: 0.469
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL296512
Similarity: 0.469
CHEMBL145460
Similarity: 0.468
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL1744040
Similarity: 0.468
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL1788196
Similarity: 0.468
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL3735756
Similarity: 0.468
CHEMBL423371
Similarity: 0.468
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL134707
Similarity: 0.468
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL185730
Similarity: 0.467
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL196893
Similarity: 0.467
CHEMBL282136
Similarity: 0.467
CHEMBL73112
Similarity: 0.466
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL73151
Similarity: 0.466
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL59464
Similarity: 0.466
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL328595
Similarity: 0.465
CHEMBL188835
Similarity: 0.465
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL113378
Similarity: 0.465
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL364592
Similarity: 0.464
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL12347
Similarity: 0.464
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL2152631
Similarity: 0.464
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL64283
Similarity: 0.464
CHEMBL142535
Similarity: 0.464
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL60840
Similarity: 0.463
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL90911
Similarity: 0.462
CHEMBL357178
Similarity: 0.462
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL198040
Similarity: 0.462
CHEMBL198041
Similarity: 0.462
CHEMBL2377445
Similarity: 0.462
CHEMBL1744039
Similarity: 0.462
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL1788197
Similarity: 0.462
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL304426
Similarity: 0.462
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL304767
Similarity: 0.462
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL307786
Similarity: 0.462
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL312525
Similarity: 0.462
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL70680
Similarity: 0.462
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL71469
Similarity: 0.462
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL71625
Similarity: 0.462
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL315655
Similarity: 0.461
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL492418
Similarity: 0.461
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL392823
Similarity: 0.460
CHEMBL398368
Similarity: 0.460
CHEMBL60185
Similarity: 0.460
CHEMBL14022
Similarity: 0.459
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL2325931
Similarity: 0.459
CHEMBL3409234
Similarity: 0.459
CHEMBL3800636
Similarity: 0.459
CHEMBL330303
Similarity: 0.459
CHEMBL309121
Similarity: 0.458
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL197839
Similarity: 0.458
CHEMBL27811
Similarity: 0.458
CHEMBL186424
Similarity: 0.458
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL365716
Similarity: 0.458
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL71640
Similarity: 0.458
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL71247
Similarity: 0.458
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL193854
Similarity: 0.458
CHEMBL13816
Similarity: 0.457
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL185631
Similarity: 0.457
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL2113667
Similarity: 0.457
CHEMBL91122
Similarity: 0.457
CHEMBL91446
Similarity: 0.457
CHEMBL276013
Similarity: 0.456
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL336390
Similarity: 0.456
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL273618
Similarity: 0.456
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL3286578
Similarity: 0.456
CHEMBL142835
Similarity: 0.455
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL3286579
Similarity: 0.455
CHEMBL13053
Similarity: 0.455
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL269419
Similarity: 0.455
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL70606
Similarity: 0.455
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL429051
Similarity: 0.454
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL256448
Similarity: 0.454
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL2325928
Similarity: 0.453
CHEMBL2325929
Similarity: 0.453
CHEMBL2325933
Similarity: 0.453
CHEMBL1087301
Similarity: 0.452
CHEMBL284644
Similarity: 0.452
CHEMBL3084510
Similarity: 0.452
CHEMBL274781
Similarity: 0.452
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL344524
Similarity: 0.451
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL189759
Similarity: 0.451
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL275873
Similarity: 0.451
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL551959
Similarity: 0.450
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL198069
Similarity: 0.450
CHEMBL13805
Similarity: 0.450
By Homology: Dopamine D2 receptor in Rattus norvegicus

CHEMBL90837
Similarity: 0.426