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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Serotonin 2a (5-HT2a) receptor HTR2A P28223 CHEMBL224 Family A G protein-coupled receptor 0.226036324558
263 / 204     
Serotonin 2b (5-HT2b) receptor HTR2B P41595 CHEMBL1833 Family A G protein-coupled receptor 0.189728914006
81 / 59     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.189728914006
167 / 128     
Serotonin 1b (5-HT1b) receptor HTR1B P28222 CHEMBL1898 Family A G protein-coupled receptor 0.144331367387
111 / 357     
Serotonin 1a (5-HT1a) receptor HTR1A P08908 CHEMBL214 Family A G protein-coupled receptor 0.135226128791
281 / 244     
Serotonin 6 (5-HT6) receptor HTR6 P50406 CHEMBL3371 Family A G protein-coupled receptor 0.0989474790405
232 / 231     
Serotonin 1d (5-HT1d) receptor HTR1D P28221 CHEMBL1983 Family A G protein-coupled receptor 0.0989474790405
78 / 387     
Serotonin 7 (5-HT7) receptor HTR7 P34969 CHEMBL3155 Family A G protein-coupled receptor 0.0989474790405
89 / 52     
Melatonin receptor 1A MTNR1A P48039 CHEMBL1945 Family A G protein-coupled receptor 0.0898720672475
9 / 190     
Melatonin receptor 1B MTNR1B P49286 CHEMBL1946 Family A G protein-coupled receptor 0.0898720672475
12 / 178     
Serotonin transporter SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.0807923867549
598 / 368     
Dopamine transporter SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.071715932485
462 / 69     
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.071715932485
479 / 47     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.0626219668353
185 / 110     
Kappa Opioid receptor OPRK1 P41145 CHEMBL237 Family A G protein-coupled receptor 0.0626219668353
117 / 63     
Alpha-2a adrenergic receptor ADRA2A P08913 CHEMBL1867 Family A G protein-coupled receptor 0.0626219668353
21 / 13     
Histamine H1 receptor HRH1 P35367 CHEMBL231 Family A G protein-coupled receptor 0.0626219668353
61 / 9     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.0626219668353
203 / 54     
Serotonin 1e (5-HT1e) receptor HTR1E P28566 CHEMBL2182 Family A G protein-coupled receptor 0.0626219668353
7 / 13     
Serotonin 5a (5-HT5a) receptor HTR5A P47898 CHEMBL3426 Family A G protein-coupled receptor 0.0535560755162
25 / 29     
Quinone reductase 2 NQO2 P16083 CHEMBL3959 Enzyme 0.0535560755162
13 / 15     
Histamine H3 receptor HRH3 Q9Y5N1 CHEMBL264 Family A G protein-coupled receptor 0.0535560755162
91 / 13     
Dopamine D1 receptor DRD1 P21728 CHEMBL2056 Family A G protein-coupled receptor 0.0535560755162
88 / 28     
Dopamine D2 receptor (by homology) DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.0535560755162
540 / 298     
Adrenergic receptor alpha-2 ADRA2C P18825 CHEMBL1916 Family A G protein-coupled receptor 0.0535560755162
32 / 11     
Alpha-2b adrenergic receptor ADRA2B P18089 CHEMBL1942 Family A G protein-coupled receptor 0.0535560755162
12 / 11     
Serotonin 4 (5-HT4) receptor HTR4 Q13639 CHEMBL1875 Family A G protein-coupled receptor 0.0535560755162
11 / 12     
Adenosine A3 receptor ADORA3 P0DMS8 CHEMBL256 Family A G protein-coupled receptor 0.0535560755162
33 / 1     
Nitric oxide synthase, inducible NOS2 P35228 CHEMBL4481 Enzyme 0.0535560755162
23 / 0     
Histamine H4 receptor HRH4 Q9H3N8 CHEMBL3759 Family A G protein-coupled receptor 0.0535560755162
48 / 0     
Neuronal acetylcholine receptor; alpha3/beta4 CHRNA3 CHRNB4 P32297 P30926 CHEMBL1907594 Ligand-gated ion channel 0.0535560755162
65 / 0     
Leukotriene A4 hydrolase LTA4H P09960 CHEMBL4618 Protease 0.0535560755162
34 / 15     
Histamine H2 receptor HRH2 P25021 CHEMBL1941 Family A G protein-coupled receptor 0.0535560755162
12 / 15     
Beta-1 adrenergic receptor ADRB1 P08588 CHEMBL213 Family A G protein-coupled receptor 0.0535560755162
6 / 28     
Acetylcholinesterase ACHE P22303 CHEMBL220 Hydrolase 0.0535560755162
16 / 70     
Cyclooxygenase-2 PTGS2 P35354 CHEMBL230 Oxidoreductase 0.0535560755162
3 / 69     
Dipeptidyl peptidase IV DPP4 P27487 CHEMBL284 Protease 0.0535560755162
296 / 0     
Dipeptidyl peptidase II DPP7 Q9UHL4 CHEMBL3976 Protease 0.0535560755162
56 / 0     
Fibroblast activation protein alpha FAP Q12884 CHEMBL4683 Protease 0.0535560755162
8 / 0     
Dipeptidyl peptidase IX DPP9 Q86TI2 CHEMBL4793 Protease 0.0535560755162
31 / 0     
Interleukin-1 receptor-associated kinase 4 IRAK4 Q9NWZ3 CHEMBL3778 Kinase 0.0535560755162
10 / 0     
Dipeptidyl peptidase VIII DPP8 Q6V1X1 CHEMBL4657 Protease 0.0535560755162
49 / 0     
Melanin-concentrating hormone receptor 1 MCHR1 Q99705 CHEMBL344 Family A G protein-coupled receptor 0.0535560755162
21 / 0     
Platelet-derived growth factor receptor PDGFRA PDGFRB P16234 P09619 CHEMBL2095189 Kinase 0.0535560755162
0 / 29     
Serotonin 3a (5-HT3a) receptor HTR3A P46098 CHEMBL1899 Ligand-gated ion channel 0.0535560755162
35 / 3     
Telomerase reverse transcriptase TERT O14746 CHEMBL2916 Enzyme 0.0535560755162
6 / 0     
c-Jun N-terminal kinase 1 MAPK8 P45983 CHEMBL2276 Kinase 0.0535560755162
3 / 0     
Cyclin-dependent kinase 9 CDK9 P50750 CHEMBL3116 Kinase 0.0535560755162
35 / 0     
PH domain leucine-rich repeat-containing protein phosphatase 2 PHLPP2 Q6ZVD8 CHEMBL1275209 Enzyme 0.0535560755162
1 / 0     
Protein arginine N-methyltransferase 6 PRMT6 Q96LA8 CHEMBL1275221 Writer 0.0535560755162
9 / 0     
Protein arginine N-methyltransferase 8 PRMT8 Q9NR22 CHEMBL3108648 Writer 0.0535560755162
8 / 0     
Protein-arginine N-methyltransferase 1 PRMT1 Q99873 CHEMBL5524 Writer 0.0535560755162
8 / 0     
Tyrosine-protein kinase JAK2 JAK2 O60674 CHEMBL2971 Kinase 0.0535560755162
17 / 0     
c-Jun N-terminal kinase 2 MAPK9 P45984 CHEMBL4179 Kinase 0.0535560755162
1 / 0     
Muscarinic acetylcholine receptor M2 CHRM2 P08172 CHEMBL211 Family A G protein-coupled receptor 0.0535560755162
95 / 0     
Muscarinic acetylcholine receptor M3 CHRM3 P20309 CHEMBL245 Family A G protein-coupled receptor 0.0535560755162
81 / 0     
Anandamide amidohydrolase FAAH O00519 CHEMBL2243 Enzyme 0.0535560755162
0 / 1     
Vascular endothelial growth factor receptor 3 FLT4 P35916 CHEMBL1955 Kinase 0.0535560755162
0 / 23     
Neuronal acetylcholine receptor protein alpha-4 subunit CHRNA4 P43681 CHEMBL1882 Ligand-gated ion channel 0.0535560755162
23 / 0     
Nuclear receptor subfamily 4 group A member 1 NR4A1 P22736 CHEMBL1293229 Nuclear receptor 0.0535560755162
1 / 0     
Serine/threonine-protein kinase PIM2 PIM2 Q9P1W9 CHEMBL4523 Kinase 0.0535560755162
44 / 0     
Epidermal growth factor receptor erbB1 EGFR P00533 CHEMBL203 Kinase 0.0535560755162
32 / 40     
Dopamine D5 receptor DRD5 P21918 CHEMBL1850 Family A G protein-coupled receptor 0.0535560755162
33 / 19     
Retinoid X receptor alpha RXRA P19793 CHEMBL2061 Nuclear receptor 0.0535560755162
1 / 0     
Serine/threonine-protein kinase Chk2 CHEK2 O96017 CHEMBL2527 Kinase 0.0535560755162
4 / 0     
PDZ-binding kinase PBK Q96KB5 CHEMBL4896 Kinase 0.0535560755162
9 / 0     
Inhibitor of apoptosis protein 3 XIAP P98170 CHEMBL4198 Other cytosolic protein 0.0535560755162
73 / 0     
Metastin receptor KISS1R Q969F8 CHEMBL5413 Family A G protein-coupled receptor 0.0535560755162
5 / 0     
Muscarinic acetylcholine receptor M4 CHRM4 P08173 CHEMBL1821 Family A G protein-coupled receptor 0.0535560755162
49 / 0     
Peptide N-myristoyltransferase 1 NMT1 P30419 CHEMBL2593 Enzyme 0.0535560755162
5 / 0     
Proto-oncogene tyrosine-protein kinase MER MERTK Q12866 CHEMBL5331 Kinase 0.0535560755162
4 / 0     
Muscarinic acetylcholine receptor M5 CHRM5 P08912 CHEMBL2035 Family A G protein-coupled receptor 0.0535560755162
67 / 0     
Baculoviral IAP repeat-containing protein 2 BIRC2 Q13490 CHEMBL5462 Enzyme 0.0535560755162
34 / 0     
Mu opioid receptor OPRM1 P35372 CHEMBL233 Family A G protein-coupled receptor 0.0535560755162
182 / 211     
Prolyl endopeptidase PREP P48147 CHEMBL3202 Protease 0.0535560755162
2 / 0     
Tyrosine-protein kinase receptor UFO AXL P30530 CHEMBL4895 Kinase 0.0535560755162
3 / 0     
Tyrosine-protein kinase receptor TYRO3 TYRO3 Q06418 CHEMBL5314 Kinase 0.0535560755162
3 / 0     
Delta opioid receptor OPRD1 P41143 CHEMBL236 Family A G protein-coupled receptor 0.0535560755162
151 / 132     
Alpha-1d adrenergic receptor ADRA1D P25100 CHEMBL223 Family A G protein-coupled receptor 0.0
46 / 20     
Alpha-1a adrenergic receptor ADRA1A P35348 CHEMBL229 Family A G protein-coupled receptor 0.0
81 / 46     
Alpha-1b adrenergic receptor ADRA1B P35368 CHEMBL232 Family A G protein-coupled receptor 0.0
66 / 18     
Myeloperoxidase MPO P05164 CHEMBL2439 Enzyme 0.0
1 / 44     
Beta-3 adrenergic receptor ADRB3 P13945 CHEMBL246 Family A G protein-coupled receptor 0.0
1 / 21     
Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3 CHRNB3 CHRNA6 CHRNB2 CHRNA3 Q05901 Q15825 P17787 P32297 CHEMBL2109233 Ligand-gated ion channel 0.0
3 / 0     
Tyrosine-protein kinase ZAP-70 ZAP70 P43403 CHEMBL2803 Kinase 0.0
1 / 0     
Nitric-oxide synthase, endothelial NOS3 P29474 CHEMBL4803 Enzyme 0.0
11 / 0     
Carnitine O-palmitoyltransferase 1, muscle isoform (by homology) CPT1B Q92523 CHEMBL2216739 Group translocator 0.0
1 / 0     
Tyrosine-protein kinase TYK2 TYK2 P29597 CHEMBL3553 Kinase 0.0
4 / 0     
Cytochrome P450 2D6 CYP2D6 P10635 CHEMBL289 Cytochrome P450 0.0
2 / 2     
Acetylcholine receptor; alpha1/beta1/delta/gamma CHRNB1 CHRNA1 CHRNG CHRND P11230 P02708 P07510 Q07001 CHEMBL1907588 Ligand-gated ion channel 0.0
7 / 0     
Histone-arginine methyltransferase CARM1 CARM1 Q86X55 CHEMBL5406 Writer 0.0
1 / 0     
Serotonin 1f (5-HT1f) receptor HTR1F P30939 CHEMBL1805 Family A G protein-coupled receptor 0.0
23 / 14     
Methionine aminopeptidase 2 METAP2 P50579 CHEMBL3922 Protease 0.0
1 / 0     
Tyrosyl-DNA phosphodiesterase 1 TDP1 Q9NUW8 CHEMBL1075138 Enzyme 0.0
2 / 0     
Ketohexokinase KHK P50053 CHEMBL1275212 Enzyme 0.0
4 / 0     
C-C motif chemokine 2 CCL2 P13500 CHEMBL1649052 Family A G protein-coupled receptor 0.0
3 / 0     
DNA-(apurinic or apyrimidinic site) lyase APEX1 P27695 CHEMBL5619 Enzyme 0.0
5 / 0     
Tyrosine-protein kinase JAK3 JAK3 P52333 CHEMBL2148 Kinase 0.0
7 / 0     
P-glycoprotein 1 ABCB1 P08183 CHEMBL4302 Primary active transporter 0.0
10 / 26     
Receptor protein-tyrosine kinase erbB-2 ERBB2 P04626 CHEMBL1824 Kinase 0.0
12 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.