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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Serotonin 1b (5-HT1b) receptor HTR1B P28222 CHEMBL1898 Family A G protein-coupled receptor 0.35007168437
576 / 65     
Serotonin 7 (5-HT7) receptor HTR7 P34969 CHEMBL3155 Family A G protein-coupled receptor 0.35007168437
851 / 15     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.323724557775
1267 / 8     
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.314979836402
4026 / 90     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.314979836402
755 / 19     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.314979836402
1621 / 20     
Serotonin 2a (5-HT2a) receptor HTR2A P28223 CHEMBL224 Family A G protein-coupled receptor 0.306239351562
1722 / 35     
Serotonin 6 (5-HT6) receptor HTR6 P50406 CHEMBL3371 Family A G protein-coupled receptor 0.306239351562
768 / 55     
Serotonin 2b (5-HT2b) receptor HTR2B P41595 CHEMBL1833 Family A G protein-coupled receptor 0.2798670472
267 / 24     
Dopamine D1 receptor DRD1 P21728 CHEMBL2056 Family A G protein-coupled receptor 0.253545671398
308 / 21     
Serotonin 1d (5-HT1d) receptor HTR1D P28221 CHEMBL1983 Family A G protein-coupled receptor 0.244789770347
523 / 61     
Serotonin 1a (5-HT1a) receptor HTR1A P08908 CHEMBL214 Family A G protein-coupled receptor 0.244789770347
1612 / 25     
Alpha-2b adrenergic receptor ADRA2B P18089 CHEMBL1942 Family A G protein-coupled receptor 0.244789770347
77 / 11     
Histamine H1 receptor HRH1 P35367 CHEMBL231 Family A G protein-coupled receptor 0.227270041604
228 / 6     
Alpha-2a adrenergic receptor ADRA2A P08913 CHEMBL1867 Family A G protein-coupled receptor 0.21849416433
100 / 12     
Dopamine D4 receptor DRD4 P21917 CHEMBL219 Family A G protein-coupled receptor 0.192104608146
952 / 8     
Dopamine D5 receptor DRD5 P21918 CHEMBL1850 Family A G protein-coupled receptor 0.174623781176
78 / 4     
Serotonin 5a (5-HT5a) receptor HTR5A P47898 CHEMBL3426 Family A G protein-coupled receptor 0.165835530515
53 / 8     
Adrenergic receptor beta ADRB2 P07550 CHEMBL210 Family A G protein-coupled receptor 0.148309680814
14 / 5     
Beta-1 adrenergic receptor ADRB1 P08588 CHEMBL213 Family A G protein-coupled receptor 0.148309680814
30 / 7     
Cytochrome P450 2D6 CYP2D6 P10635 CHEMBL289 Cytochrome P450 0.113206574926
12 / 4     
Serotonin 1e (5-HT1e) receptor HTR1E P28566 CHEMBL2182 Family A G protein-coupled receptor 0.113206574926
11 / 6     
C-X-C chemokine receptor type 3 CXCR3 P49682 CHEMBL4441 Family A G protein-coupled receptor 0.104440650707
82 / 55     
Adrenergic receptor alpha-2 ADRA2C P18825 CHEMBL1916 Family A G protein-coupled receptor 0.0
89 / 9     
Alpha-1d adrenergic receptor ADRA1D P25100 CHEMBL223 Family A G protein-coupled receptor 0.0
401 / 8     
Alpha-1a adrenergic receptor ADRA1A P35348 CHEMBL229 Family A G protein-coupled receptor 0.0
721 / 8     
Phosphodiesterase 10A PDE10A Q9Y233 CHEMBL4409 Phosphodiesterase 0.0
100 / 0     
Lysosomal Pro-X carboxypeptidase PRCP P42785 CHEMBL2335 Protease 0.0
173 / 0     
Sphingosine 1-phosphate receptor Edg-3 S1PR3 Q99500 CHEMBL3892 Family A G protein-coupled receptor 0.0
23 / 0     
Acetyl-CoA carboxylase 2 ACACB O00763 CHEMBL4829 Ligase 0.0
96 / 0     
Scavenger receptor class B member 1 SCARB1 Q8WTV0 CHEMBL1914272 Unclassified protein 0.0
7 / 0     
Glucocorticoid receptor NR3C1 P04150 CHEMBL2034 Nuclear receptor 0.0
42 / 0     
C-C chemokine receptor type 5 CCR5 P51681 CHEMBL274 Family A G protein-coupled receptor 0.0
591 / 0     
C-C chemokine receptor type 3 CCR3 P51677 CHEMBL3473 Family A G protein-coupled receptor 0.0
456 / 0     
Phosphodiesterase 9A PDE9A O76083 CHEMBL3535 Phosphodiesterase 0.0
14 / 0     
Phosphodiesterase 1C PDE1C Q14123 CHEMBL4619 Phosphodiesterase 0.0
12 / 0     
P-glycoprotein 1 ABCB1 P08183 CHEMBL4302 Primary active transporter 0.0
160 / 0     
Neuropeptides B/W receptor type 1 (by homology) NPBWR1 P48145 CHEMBL1293293 Family A G protein-coupled receptor 0.0
26 / 0     
Muscarinic acetylcholine receptor M1 (by homology) CHRM1 P11229 CHEMBL216 Family A G protein-coupled receptor 0.0
524 / 0     
Glycine transporter 1 SLC6A9 P48067 CHEMBL2337 Electrochemical transporter 0.0
80 / 0     
Glycine transporter 2 SLC6A5 Q9Y345 CHEMBL3060 Electrochemical transporter 0.0
46 / 0     
Gonadotropin-releasing hormone receptor GNRHR P30968 CHEMBL1855 Family A G protein-coupled receptor 0.0
417 / 0     
Dipeptidyl peptidase IV DPP4 P27487 CHEMBL284 Protease 0.0
1794 / 0     
Cathepsin S CTSS P25774 CHEMBL2954 Protease 0.0
40 / 0     
Muscarinic acetylcholine receptor M2 CHRM2 P08172 CHEMBL211 Family A G protein-coupled receptor 0.0
453 / 0     
Multidrug resistance-associated protein 1 ABCC1 P33527 CHEMBL3004 Primary active transporter 0.0
74 / 0     
Serotonin 1f (5-HT1f) receptor HTR1F P30939 CHEMBL1805 Family A G protein-coupled receptor 0.0
91 / 0     
Tyrosine-protein kinase SYK SYK P43405 CHEMBL2599 Kinase 0.0
313 / 0     
Tyrosine-protein kinase ITK/TSK ITK Q08881 CHEMBL2959 Kinase 0.0
111 / 0     
Serine/threonine-protein kinase Aurora-A AURKA O14965 CHEMBL4722 Kinase 0.0
316 / 0     
Tyrosine-protein kinase ABL ABL1 P00519 CHEMBL1862 Kinase 0.0
82 / 0     
Rho-associated protein kinase 2 ROCK2 O75116 CHEMBL2973 Kinase 0.0
390 / 0     
Melanin-concentrating hormone receptor 1 MCHR1 Q99705 CHEMBL344 Family A G protein-coupled receptor 0.0
690 / 0     
Orexin receptor 2 HCRTR2 O43614 CHEMBL4792 Family A G protein-coupled receptor 0.0
35 / 0     
Orexin receptor 1 HCRTR1 O43613 CHEMBL5113 Family A G protein-coupled receptor 0.0
33 / 0     
Histamine H2 receptor HRH2 P25021 CHEMBL1941 Family A G protein-coupled receptor 0.0
34 / 2     
Transcriptional regulator ERG ERG P11308 CHEMBL1293191 Unclassified protein 0.0
16 / 0     
Phospholipase D1 PLD1 Q13393 CHEMBL2536 Hydrolase 0.0
71 / 0     
Phospholipase D2 PLD2 O14939 CHEMBL2734 Hydrolase 0.0
60 / 0     
ATP-sensitive inward rectifier potassium channel 1 KCNJ1 P48048 CHEMBL1293292 Voltage-gated ion channel 0.0
20 / 0     
C-X-C chemokine receptor type 7 ACKR3 P25106 CHEMBL2010631 Family A G protein-coupled receptor 0.0
33 / 0     
Inhibitor of apoptosis protein 3 XIAP P98170 CHEMBL4198 Other cytosolic protein 0.0
391 / 0     
Mu opioid receptor OPRM1 P35372 CHEMBL233 Family A G protein-coupled receptor 0.0
2191 / 43     
Cyclin-dependent kinase 2/cyclin A CDK2 CCNA1 CCNA2 P24941 P78396 P20248 CHEMBL2094128 Other cytosolic protein 0.0
95 / 0     
Heat shock protein HSP 90-alpha HSP90AA1 P07900 CHEMBL3880 Other cytosolic protein 0.0
77 / 0     
Muscarinic acetylcholine receptor M3 (by homology) CHRM3 P20309 CHEMBL245 Family A G protein-coupled receptor 0.0
342 / 0     
Dipeptidyl peptidase II DPP7 Q9UHL4 CHEMBL3976 Protease 0.0
299 / 0     
Receptor protein-tyrosine kinase erbB-2 ERBB2 P04626 CHEMBL1824 Kinase 0.0
143 / 0     
Max-like protein X MLX Q9UH92 CHEMBL2062357 Unclassified protein 0.0
7 / 0     
Adenosine kinase ADK P55263 CHEMBL3589 Enzyme 0.0
15 / 0     
Cystic fibrosis transmembrane conductance regulator CFTR P13569 CHEMBL4051 Other ion channel 0.0
9 / 0     
Serine/threonine-protein kinase PAK 4 PAK4 O96013 CHEMBL4482 Kinase 0.0
45 / 0     
Leukotriene A4 hydrolase LTA4H P09960 CHEMBL4618 Protease 0.0
154 / 0     
Synaptic vesicular amine transporter (by homology) SLC18A2 Q05940 CHEMBL1893 Electrochemical transporter 0.0
51 / 0     
Nucleotide-binding oligomerization domain-containing protein 1 NOD1 Q9Y239 CHEMBL1293222 Unclassified protein 0.0
12 / 0     
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Q9HC29 CHEMBL1293266 Unclassified protein 0.0
11 / 0     
Voltage-gated T-type calcium channel alpha-1H subunit CACNA1H O95180 CHEMBL1859 Voltage-gated ion channel 0.0
27 / 0     
DNA-directed RNA polymerase I subunit RPA1 POLR1A O95602 CHEMBL3286067 Enzyme 0.0
15 / 0     
Kinesin-like protein 1 KIF11 P52732 CHEMBL4581 Other cytosolic protein 0.0
189 / 0     
C-C chemokine receptor type 8 CCR8 P51685 CHEMBL4596 Family A G protein-coupled receptor 0.0
13 / 0     
Smoothened homolog SMO Q99835 CHEMBL5971 Frizzled family G protein-coupled receptor 0.0
23 / 0     
Tyrosine-protein kinase LCK LCK P06239 CHEMBL258 Kinase 0.0
85 / 3     
Beta-secretase 1 BACE1 P56817 CHEMBL4822 Protease 0.0
167 / 0     
Cytochrome P450 26A1 CYP26A1 O43174 CHEMBL5141 Cytochrome P450 0.0
9 / 0     
Lanosterol synthase LSS P48449 CHEMBL3593 Enzyme 0.0
50 / 0     
Cathepsin K CTSK P43235 CHEMBL268 Protease 0.0
47 / 0     
Nitric oxide synthase, inducible (by homology) NOS2 P35228 CHEMBL4481 Enzyme 0.0
160 / 0     
EZH2/SUZ12/EED/RBBP7/RBBP4 EZH2 Q15910 CHEMBL2189110 Writer 0.0
31 / 0     
Sphingosine-1-phosphate lyase 1 SGPL1 O95470 CHEMBL3286061 Enzyme 0.0
13 / 0     
Acetyl-CoA carboxylase 1 ACACA Q13085 CHEMBL3351 Enzyme 0.0
50 / 0     
MAP kinase ERK2 (by homology) MAPK1 P28482 CHEMBL4040 Kinase 0.0
204 / 0     
Nuclear receptor subfamily 1 group I member 3 NR1I3 Q14994 CHEMBL5503 Nuclear receptor 0.0
23 / 0     
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 Q9Y3Q4 CHEMBL1250417 Voltage-gated ion channel 0.0
20 / 0     
C-C motif chemokine 5 CCL5 P13501 CHEMBL1275217 Family A G protein-coupled receptor 0.0
24 / 0     
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 HCN1 O60741 CHEMBL1795171 Voltage-gated ion channel 0.0
22 / 0     
C-C chemokine receptor-like 2 CCRL2 O00421 CHEMBL2321627 Family A G protein-coupled receptor 0.0
1 / 0     
Urotensin II receptor UTS2R Q9UKP6 CHEMBL3764 Family A G protein-coupled receptor 0.0
137 / 0     
Peregrin BRPF1 P55201 CHEMBL3132741 Reader 0.0
12 / 0     
Tissue-type plasminogen activator PLAT P00750 CHEMBL1873 Protease 0.0
17 / 0     
Muscarinic acetylcholine receptor M5 CHRM5 P08912 CHEMBL2035 Family A G protein-coupled receptor 0.0
143 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.