In order to avoid security-related warning messages when switching to secured connection, you may want either to:

Click here to proceed.

Query Molecule
Target Classes
Top 15
Top 25
Top 50
All
Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Serotonin 2b (5-HT2b) receptor HTR2B P41595 CHEMBL1833 Family A G protein-coupled receptor 0.104440650707
172 / 38     
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.0
2176 / 373     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.0
877 / 115     
Acetylcholinesterase ACHE P22303 CHEMBL220 Hydrolase 0.0
478 / 91     
Serotonin 1a (5-HT1a) receptor HTR1A P08908 CHEMBL214 Family A G protein-coupled receptor 0.0
987 / 167     
Serotonin 2a (5-HT2a) receptor HTR2A P28223 CHEMBL224 Family A G protein-coupled receptor 0.0
1073 / 147     
Alpha-2a adrenergic receptor ADRA2A P08913 CHEMBL1867 Family A G protein-coupled receptor 0.0
110 / 28     
Adrenergic receptor alpha-2 ADRA2C P18825 CHEMBL1916 Family A G protein-coupled receptor 0.0
102 / 21     
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.0
191 / 43     
Serotonin transporter SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.0
1398 / 261     
Dopamine transporter SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.0
832 / 76     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.0
491 / 80     
Serotonin 7 (5-HT7) receptor HTR7 P34969 CHEMBL3155 Family A G protein-coupled receptor 0.0
417 / 41     
Serotonin 6 (5-HT6) receptor HTR6 P50406 CHEMBL3371 Family A G protein-coupled receptor 0.0
352 / 134     
Alpha-1d adrenergic receptor ADRA1D P25100 CHEMBL223 Family A G protein-coupled receptor 0.0
318 / 15     
Alpha-1a adrenergic receptor ADRA1A P35348 CHEMBL229 Family A G protein-coupled receptor 0.0
576 / 40     
Histamine H1 receptor HRH1 P35367 CHEMBL231 Family A G protein-coupled receptor 0.0
115 / 14     
Alpha-2b adrenergic receptor ADRA2B P18089 CHEMBL1942 Family A G protein-coupled receptor 0.0
90 / 27     
Serotonin 1b (5-HT1b) receptor HTR1B P28222 CHEMBL1898 Family A G protein-coupled receptor 0.0
279 / 349     
Dopamine D1 receptor DRD1 P21728 CHEMBL2056 Family A G protein-coupled receptor 0.0
155 / 31     
Neurokinin 2 receptor TACR2 P21452 CHEMBL2327 Family A G protein-coupled receptor 0.0
136 / 116     
Histamine H2 receptor HRH2 P25021 CHEMBL1941 Family A G protein-coupled receptor 0.0
23 / 20     
Serine/threonine-protein kinase PAK 4 PAK4 O96013 CHEMBL4482 Kinase 0.0
62 / 0     
Proteinase-activated receptor 1 F2R P25116 CHEMBL3974 Family A G protein-coupled receptor 0.0
36 / 0     
Tyrosine-protein kinase JAK1 JAK1 P23458 CHEMBL2835 Kinase 0.0
174 / 0     
Ghrelin receptor GHSR Q92847 CHEMBL4616 Family A G protein-coupled receptor 0.0
197 / 47     
Dipeptidyl peptidase IX DPP9 Q86TI2 CHEMBL4793 Protease 0.0
142 / 0     
Cytochrome P450 2D6 CYP2D6 P10635 CHEMBL289 Cytochrome P450 0.0
5 / 4     
Serine/threonine-protein kinase PAK 3 PAK3 O75914 CHEMBL2999 Kinase 0.0
5 / 0     
Serine/threonine-protein kinase PAK6 PAK6 Q9NQU5 CHEMBL4311 Kinase 0.0
5 / 0     
Serine/threonine-protein kinase PAK 2 PAK2 Q13177 CHEMBL4487 Kinase 0.0
5 / 0     
Serine/threonine-protein kinase PAK7 PAK5 Q9P286 CHEMBL4524 Kinase 0.0
6 / 0     
Serine/threonine-protein kinase PAK 1 PAK1 Q13153 CHEMBL4600 Kinase 0.0
30 / 0     
Cyclin-dependent kinase 2/cyclin A CDK2 CCNA1 CCNA2 P24941 P78396 P20248 CHEMBL2094128 Other cytosolic protein 0.0
96 / 0     
MAP kinase ERK2 (by homology) MAPK1 P28482 CHEMBL4040 Kinase 0.0
185 / 0     
HERG KCNH2 Q12809 CHEMBL240 Voltage-gated ion channel 0.0
767 / 76     
Lysosomal Pro-X carboxypeptidase PRCP P42785 CHEMBL2335 Protease 0.0
176 / 0     
G-protein coupled bile acid receptor 1 GPBAR1 Q8TDU6 CHEMBL5409 Family A G protein-coupled receptor 0.0
0 / 1     
Opioid growth factor receptor-like protein 1 OGFRL1 Q5TC84 CHEMBL3638334 Unclassified protein 0.0
11 / 0     
MAP kinase ERK1 (by homology) MAPK3 P27361 CHEMBL3385 Kinase 0.0
51 / 0     
Somatostatin receptor 2 (by homology) SSTR2 P30874 CHEMBL1804 Family A G protein-coupled receptor 0.0
57 / 109     
Serotonin 5a (5-HT5a) receptor HTR5A P47898 CHEMBL3426 Family A G protein-coupled receptor 0.0
12 / 10     
Voltage-gated T-type calcium channel alpha-1G subunit CACNA1G O43497 CHEMBL4641 Voltage-gated ion channel 0.0
97 / 0     
EZH2/SUZ12/EED/RBBP7/RBBP4 EZH2 Q15910 CHEMBL2189110 Writer 0.0
26 / 0     
Stem cell growth factor receptor KIT P10721 CHEMBL1936 Kinase 0.0
96 / 0     
Serine/threonine-protein kinase Aurora-B AURKB Q96GD4 CHEMBL2185 Kinase 0.0
137 / 0     
MAP kinase p38 beta MAPK11 Q15759 CHEMBL3961 Kinase 0.0
14 / 0     
PDZ-binding kinase PBK Q96KB5 CHEMBL4896 Kinase 0.0
53 / 0     
Dopamine D4 receptor DRD4 P21917 CHEMBL219 Family A G protein-coupled receptor 0.0
468 / 28     
Sigma opioid receptor (by homology) SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.0
728 / 79     
Coagulation factor V F5 P12259 CHEMBL3618 Secreted protein 0.0
1 / 0     
Voltage-gated T-type calcium channel alpha-1I subunit CACNA1I Q9P0X4 CHEMBL5558 Voltage-gated ion channel 0.0
17 / 0     
Dipeptidyl peptidase II DPP7 Q9UHL4 CHEMBL3976 Protease 0.0
171 / 0     
Serine/threonine-protein kinase B-raf BRAF P15056 CHEMBL5145 Kinase 0.0
90 / 0     
Lysine-specific histone demethylase 1 KDM1A O60341 CHEMBL6136 Eraser 0.0
30 / 0     
C-X-C chemokine receptor type 7 ACKR3 P25106 CHEMBL2010631 Family A G protein-coupled receptor 0.0
34 / 0     
Adenosine kinase ADK P55263 CHEMBL3589 Enzyme 0.0
16 / 0     
Interleukin-1 receptor-associated kinase 4 IRAK4 Q9NWZ3 CHEMBL3778 Kinase 0.0
55 / 0     
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 Q9Y3Q4 CHEMBL1250417 Voltage-gated ion channel 0.0
15 / 0     
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (by homology) HCN1 O60741 CHEMBL1795171 Voltage-gated ion channel 0.0
17 / 0     
MAP kinase-activated protein kinase 2 MAPKAPK2 P49137 CHEMBL2208 Kinase 0.0
159 / 0     
Cyclin-dependent kinase 9 CDK9 P50750 CHEMBL3116 Kinase 0.0
58 / 0     
Neurokinin 1 receptor TACR1 P25103 CHEMBL249 Family A G protein-coupled receptor 0.0
256 / 237     
High-affinity choline transporter SLC5A7 Q9GZV3 CHEMBL4507 Electrochemical transporter 0.0
18 / 0     
Sonic hedgehog protein (by homology) SHH Q15465 CHEMBL5602 Unclassified protein 0.0
5 / 0     
Interleukin-8 receptor A CXCR1 P25024 CHEMBL4029 Family A G protein-coupled receptor 0.0
12 / 0     
Fatty acid synthase FASN P49327 CHEMBL4158 Transferase 0.0
17 / 0     
Tissue-type plasminogen activator PLAT P00750 CHEMBL1873 Protease 0.0
12 / 0     
Serine/threonine-protein kinase AKT2 AKT2 P31751 CHEMBL2431 Kinase 0.0
49 / 0     
Phosphodiesterase 4B PDE4B Q07343 CHEMBL275 Phosphodiesterase 0.0
29 / 0     
Phosphodiesterase 7A PDE7A Q13946 CHEMBL3012 Phosphodiesterase 0.0
21 / 0     
LIM domain kinase 1 LIMK1 P53667 CHEMBL3836 Kinase 0.0
43 / 0     
Dual specificity protein kinase TTK TTK P33981 CHEMBL3983 Kinase 0.0
22 / 0     
Serine/threonine-protein kinase AKT AKT3 Q9Y243 CHEMBL4816 Kinase 0.0
41 / 0     
LIM domain kinase 2 LIMK2 P53671 CHEMBL5932 Kinase 0.0
32 / 0     
Leucine-rich repeat serine/threonine-protein kinase 2 LRRK2 Q5S007 CHEMBL1075104 Kinase 0.0
17 / 0     
G protein-coupled receptor kinase 7 GRK7 Q8WTQ7 CHEMBL1075133 Kinase 0.0
6 / 0     
Serine/threonine-protein kinase 38 STK38 Q15208 CHEMBL1075155 Kinase 0.0
2 / 0     
Homeodomain-interacting protein kinase 4 HIPK4 Q8NE63 CHEMBL1075167 Kinase 0.0
7 / 0     
Serine/threonine-protein kinase/endoribonuclease IRE1 ERN1 O75460 CHEMBL1163101 Enzyme 0.0
5 / 0     
Serine/threonine-protein kinase OSR1 OXSR1 O95747 CHEMBL1163104 Kinase 0.0
4 / 0     
STE20/SPS1-related proline-alanine-rich protein kinase STK39 Q9UEW8 CHEMBL1163108 Kinase 0.0
4 / 0     
U4/U6 small nuclear ribonucleoprotein Prp4 PRPF4 O43172 CHEMBL1163119 Other nuclear protein 0.0
1 / 0     
Mitogen-activated protein kinase kinase kinase 13 MAP3K13 O43283 CHEMBL1163124 Kinase 0.0
5 / 0     
Serine/threonine-protein kinase ICK ICK Q9UPZ9 CHEMBL1163126 Kinase 0.0
4 / 0     
Mitogen-activated protein kinase kinase kinase 15 MAP3K15 Q6ZN16 CHEMBL1163127 Kinase 0.0
3 / 0     
Microtubule-associated serine/threonine-protein kinase 1 MAST1 Q9Y2H9 CHEMBL1163128 Kinase 0.0
5 / 0     
Serine/threonine-protein kinase SBK1 SBK1 Q52WX2 CHEMBL1163129 Kinase 0.0
3 / 0     
Hormonally up-regulated neu tumor-associated kinase HUNK P57058 CHEMBL1795165 Enzyme 0.0
4 / 0     
Tyrosine-protein kinase FYN FYN P06241 CHEMBL1841 Kinase 0.0
32 / 0     
Tyrosine-protein kinase ABL ABL1 P00519 CHEMBL1862 Kinase 0.0
100 / 0     
Serine/threonine-protein kinase PRP4 homolog PRPF4B Q13523 CHEMBL1908382 Enzyme 0.0
4 / 0     
SNF-related serine/threonine-protein kinase SNRK Q9NRH2 CHEMBL1908384 Enzyme 0.0
2 / 0     
Dual serine/threonine and tyrosine protein kinase DSTYK Q6XUX3 CHEMBL1908386 Enzyme 0.0
5 / 0     
Mitogen-activated protein kinase kinase kinase 12 MAP3K12 Q12852 CHEMBL1908389 Enzyme 0.0
45 / 0     
Insulin receptor INSR P06213 CHEMBL1981 Kinase 0.0
38 / 0     
Tyrosine-protein kinase YES YES1 P07947 CHEMBL2073 Kinase 0.0
22 / 0     
Platelet-derived growth factor receptor PDGFRA PDGFRB P16234 P09619 CHEMBL2095189 Kinase 0.0
10 / 0     
Dual specificity mitogen-activated protein kinase kinase 3 MAP2K3 P46734 CHEMBL2109 Kinase 0.0
5 / 0     
AMP-activated protein kinase, alpha-2 subunit PRKAA2 P54646 CHEMBL2116 Kinase 0.0
3 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.